immunoglobulin M

GC: n

S: NHS – (last access: 21 July 2020); NIH – (last access: 21 July 2020).

N: 1. First Known Use of immunoglobulin (immune + globulin): 1953.
immunoglobulin: antibody. The glycoproteins produced by B-cells, called antibodies or immunoglobulins, recognize and bind free antigens and are responsible for humoral immunity…
2. The class of immunoglobulins which is active against bacteria or erythrocytes and in certain pathologic states may be active against autologous antibody […] Because of its size, it does not cross the placenta barrier in man.
3. [A] large pentameric immunoglobulin [molecule] (five linked subunits), largely confined to plasma [that is] produced early in response to infecting organisms …
4. Antibodies are grouped into five classes according to their constant region. Each class is designated by a letter attached to an abbreviation of the word immunoglobulin: IgG, IgM, IgA, IgD, and IgE. The classes of antibody differ not only in their constant region but also in activity. For example, IgG, the most common antibody, is present mostly in the blood and tissue fluids, while IgA is found in the mucous membranes lining the respiratory and gastrointestinal tracts.

S: 1. MW –; (last access: 21 July 2020); OED – (last access: 21 July 2020). 2. GDT – (last access: 21 July 2020). 3. TERMIUM PLUS – (last access: 21 July 2020). 4. EncBrit – (last access: 21 July 2020).

SYN: IgM, IgM antibody.

S: TERMIUM PLUS – (last access: 21 July 2020)

CR: antibody, coronavirus, COVID-19, polymerase chain reaction, serological test, serology, T cell.