GC: n
S: NCBI – https://pubmed.ncbi.nlm.nih.gov/8383578/ (last access: 1 August 2021); ACSJ – https://acsjournals.onlinelibrary.wiley.com/doi/abs/10.1002/1097-0142%2819930301%2971%3A5%3C1741%3A%3AAID-CNCR2820710507%3E3.0.CO%3B2-Q (last access: 1 August 2021).
N: 1. anti- + aggregant.
– Adjective. antiaggregant (comparative more antiaggregant, superlative most antiaggregant). Medicine: That prevents the aggregation of platelets; antiplatelet.
– Noun. antiaggregant (plural antiaggregants). Medicine: Any drug that prevents the aggregation of platelets.
2. antiaggregating, anti-aggregating (adjective). A correlated study of both the structure and the function of the platelet would appear to be necessary in the evaluation of antiaggregating chemical agents.
3. Aspirin indication in primary prevention has been questioned in the last ten years due to the publica-tion of several trials with neutral outcomes. In the last year, three research studies discussed in thisreview (ASCEND, ARRIVE, ASPREE) have weighed the benefit (cardiovascular events reduction) againstthe adverse effects (especially bleeding) in several situations such as general population with moderatecardiovascular risk, diabetics and elderly population. This review performs a detailed analysis of thesetrials and it also comments on a recent metanalysis that includes these projects along with others under-taken in the last 30 years. In addition, the current position of aspirin in primary prevention is establishedbased on the latest evidence reviewed.
S: 1. Wiktionary – https://en.wiktionary.org/wiki/antiaggregant (last access: 1 August 2021). 2. TERMIUM PLUS – https://www.btb.termiumplus.gc.ca/tpv2alpha/alpha-eng.html?lang=eng&i=1&srchtxt=antiagr%C3%A9gant&codom2nd_wet=1#resultrecs (last access: 1 August 2021). 3. Elsevier – https://www.elsevier.es/en-revista-medicina-clinica-english-edition–462-articulo-the-role-aspirin-as-antiaggregant-S2387020619304152 (last access: 1 August 2021).
SYN: platelet suppressive agent
S: GDT – http://gdt.oqlf.gouv.qc.ca/ficheOqlf.aspx?Id_Fiche=8446064 (last access: 1 August 2021)
CR: anticoagulant, drug substance, platelet, thrombocytopenia, thrombosis.
