chloroquine
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GC: n

S: CNM – http://icmr.nic.in/ijmr/2008/april/0404.pdf. (last access: 4 December 2013); PCU – Patient.co.uk – http://www.patient.co.uk/medicine/chloroquine (last access: 4 December 2013).

N: 1. Chloroquine (CHQ) is a cheap, relatively well tolerated drug initially developed for the treatment of malaria in the 1930s. CHQ has, however, since accrued a plethora of uses in the treatment and amelioration of several other diseases and conditions because of its lysosomotropic properties. It also has characteristic physiological and systemic effects.
2. Chloroquine is mainly used to prevent malaria. It can be used on its own or in combination with another antimalarial to increase its effectiveness. It can also be used to treat some forms of malaria. It is not prescribable on the NHS in order to prevent malaria, but you are able to buy the tablets at pharmacies, without a prescription, for this purpose. Is available on prescription to treat rheumatoid arthritis and lupus erythematosus, although other treatments are usually preferred. These are both autoimmune diseases. This means that your immune system (which normally protects your body from infections) mistakenly attacks itself. This causes pain and damage to parts of your body. Chloroquine is used in some people to help reduce the damage caused.
3. Synthetic drug used in the treatment of malaria. Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. It also can be given by intramuscular injection as chloroquine hydrochloride. Chloroquine is effective against susceptible strains of the malarial parasites Plasmodium vivax, P. ovale, and P. falciparum, as well as certain parasitic worms and amoebas.

S: 1. CNM – http://icmr.nic.in/ijmr/2008/april/0404.pdf. (last access: 4 December 2013). 2. PCU – Patient.co.uk – http://www.patient.co.uk/medicine/chloroquine (last access: 4 December 2013). 3. EncBrit – http://global.britannica.com/science/chloroquine (last access: 7 July 2015).

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CR: chlorine, malaria.