GC: n
S: http://www.historyofvaccines.org/content/articles/human-cell-strains-vaccine-development (last access: 31 July 2015); http://www.fisher.co.uk/index.php/en/technical-support?catid=2&view=faq&faqid=32 (last access: 31 July 2015);
N: 1. – cell (n): early 12c., “small monastery, subordinate monastery” (from Medieval Latin in this sense), later “small room for a monk or a nun in a monastic establishment; a hermit’s dwelling” (c. 1300), from Latin cella “small room, store room, hut,” related to Latin celare “to hide, conceal.” Sense of monastic rooms extended to prison rooms (1722). Used in 14c., figuratively, of brain “compartments;” used in biology by 17c. of various cavities (wood structure, segments of fruit, bee combs), gradually focusing to the modern sense of “basic structure of living organisms” (which Oxford English Dictionary dates to 1845).
– strain (n): “line of descent, lineage, breed, ancestry,” c. 1200, from Old English strion, streon “a gain, acquisition, treasure; a begetting, procreation,” from Proto-Germanic *streu-nam- “to pile up,” from PIE root *stere- “to spread, extend, stretch out”. Hence “race, stock, line” (early 14c.). Applied to animal species from c. 1600; usually involving fairly minor variations, but not distinct from breed (n.). Normal sound development would have yielded *streen, but the word was altered in late Middle English, apparently by influence of strain (“injury caused by straining,” c. 1400, from strain (v.)).
2. A population of animal cells that develops from a primary culture by reseeding serially; the number of transfers is usually limited.
The characteristics of the parent cell are retained in culture.
3. The terms “cell strain” and “cell line” are sometimes used interchangeably. In this article, “cell strain” is used to describe a culture of a single type of cell; “cell line” is used to describe an immortalized culture of a single type of cell – that is, one that replicates infinitely, like the well-known HeLa cell line that was started with cancer cells taken from Henrietta Lacks.
N: 1. OED – http://www.etymonline.com/index.php?allowed_in_frame=0&search=cell+strain (last access: 17 November 2016). 2. GDT – http://gdt.oqlf.gouv.qc.ca/ficheOqlf.aspx?Id_Fiche=17041345 (last access: 31 July 2015); TERMIUM PLUS – http://goo.gl/mgw47t (last access: 31 July 2015). 3. http://www.historyofvaccines.org/content/articles/human-cell-strains-vaccine-development (last access: 31 July 2015) (last access: 31 July 2015).
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