GC: n
S: SDir – https://www.sciencedirect.com/topics/medicine-and-dentistry/thebaine (last access: 11 December 2024); NIH – https://pubchem.ncbi.nlm.nih.gov/compound/Thebaine (last access: 11 December 2024).
N: 1. From Ancient Greek Θῆβαι (Thêbai, “Thebes”) + -ine (also -in, adjectival word-forming element, Middle English, from Old French -in/-ine, or directly from Latin suffix -inus/-ina/-inum “of, like,” forming adjectives and derived nouns, as in divinus, feminus, caninus; from PIE adjectival suffix *-no- ).
2. A poisonous crystalline alkaloid C19H21NO3 found in opium in small quantities, related chemically to morphine and codeine, and possessing a sharp astringent taste and a tetanic action like strychnine.
3. Thebaine (C19H21NO3) is codeine methyl enol ether (Fig. 8.8C) present in low concentration in opium. Thebaine has no therapeutic utility but is converted to a host of compounds including butorphanol, oxycodone, oxymorphone, hydrocodone, and naloxone. Oripavine is a major metabolite of thebaine.
S: 1. Wiktionary – https://en.wiktionary.org/wiki/thebaine (last access: 11 December 2024); Etymonline – https://www.etymonline.com/search?q=-ine (last access: 11 December 2024)). 2. MW – https://www.merriam-webster.com/medical/thebaine (last access: 11 December 2024). 3. SDir – https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/thebaine (last access: 11 December 2024).
SYN:
S:
CR: opium, papaverine.
