GC: n

S: WHO – https://www.who.int/news-room/fact-sheets/detail/buruli-ulcer-(mycobacterium-ulcerans-infection) (last access: 22 June 2024); CDC – https://wwwnc.cdc.gov/eid/article/29/10/23-0011_article (last access: 22 June 2024).

N: – Buruli (prn): Buruli ulcer was first described by Sir Albert Cook in patients from Buruli County in Uganda, and the causative organism was isolated in 1948 by MacCallum in the Bairnsdale region of Victoria, Australia.

– ulcer (n): From Vulgar Latin ulcerem, from Latin ulcus (genitive ulceris) “ulcer, a sore,” figuratively “painful subject,” from PIE elk-es- “wound”.

. Abbreviation: BU.

2. Buruli ulcer (BU) is a neglected, debilitating skin disease caused by infection with Mycobacterium ulcerans. After the first definite description in 1948, M. ulcerans infections have been reported from 34 countries, mainly with tropical and subtropical climates. Following a peak of 5954 reported BU cases globally in 2004 the number of new recorded cases has been decreasing over the past years. In 2016, a total of 1952 BU cases were reported to the World Health Organization (WHO) from twelve different countries.

3. The first description of chronic skin ulcers consistent with the pathology of Mycobacterium ulcerans infection dates back to the end of the nineteenth century, when the British physician Albert Cook recorded his observations in The Mengo Hospital Notes, maintained in the library of the hospital in Kampala, Uganda.

S: 1. Medscape – https://emedicine.medscape.com/article/1104891-overview?form=fpf (last access: 22 June 2024); Etymonline – http://www.etymonline.com/index.php?allowed_in_frame=0&search=ulcer&searchmode=none  (last access: 22 June 2024); CDC – https://wwwnc.cdc.gov/eid/article/29/10/23-0011_article (last access: 22 June 2024). 2&3. NIH – https://www.ncbi.nlm.nih.gov/books/NBK553836/ (last access: 22 June 2024).

SYN: Bairnsdale ulcer

S: NCBI – https://www.ncbi.nlm.nih.gov/books/NBK553830/ (last access: 22 June 2024)

CR: leprosy, tuberculosis, ulcer.