Sjögren syndrome

GC: n

S: NIH – (last access: 21 May 2017); Medscape – (last access: 4 April 2018).

N: 1. – Sjögren (pn): Henrik Samuel Conrad Sjögren was a Swedish ophthalmologist (1899 – 1986).
– syndrome (n): “A number of symptoms occurring together,” 1540s, from medical Latin, from Greek syndrome “concurrence of symptoms, concourse of people,” from syndromos “place where several roads meet,” literally “a running together,” from syn– “with” + dromos “a running, course”. Psychological sense is from 1955.
2. A chronic autoimmune disease characterised by the occurrence of xerostomia, pharyngolaryngitis sicca, rhinitis sicca, enlarged salivary glands, keratoconjunctivitis sicca, a dry mouth, dry skin, decreased sweating, dryness and crusting of the nasal passages, blocking of the eustachian tubes which can cause deafness, vaginal dryness which can cause dyspareunia, a patchy alopecia, decrease of scalp and body hair, areas of hyperpigmentation and hypopigmentation of the skin, vasculitis, purpura, cataracts, and Raynaud syndrome. Prevalent in postmenopausal women (80-90 %) or younger women after artificial menopause. Connective tissue changes include a rheumatoid type of polyarthritis.
3.. Symptoms: Dry eyes, dry mouth, joint pain, swelling and stiffness, swollen salivary glands – particularly the set located behind your jaw and in front of your ears, skin rashes or dry skin, vaginal dryness, persistent dry cough, prolonged fatigue.
4. Causes: Joints, thyroid, kidneys, liver, lungs, skin, nerves.
5. Alternative names: Xerostomia-Sjögren syndrome, Keratoconjunctivitis sicca – Sjögren, Sicca syndrome.
6. Cultural Interrelation:
– Reality: We could mention that on 1925 Henrik Samuel Conrad Sjögren became employed at the Serafimerlasarettet, where he first met a patient with “his” syndrome, a 49 year old woman.
– Fiction: We could mention episode 5 Lucky Thirteen from the TV series (2004-2012) House M. D. (season 5).

S: . 1. OED – (last access: 17 May 2017); WNMDT – (last access: 18 May 2017). 2. WNMDT – (last access: 18 May 2017). 3 & 4. MAYO – (last access: 18 May 2017). 5. MEDLP – (last access: 18 May 2017). 6. WNMDT – (last access: 18 May 2017); (last access: 3 April 2018).

SYN: dacryosialoadenopathia atrophicans, gougerot-houwer-sjogren syndrome, gougerot-sjogren syndrome, keratoconjunctivitis sicca, keratoconjunctivitis sicca-xerostomia, secreto-inhibitor-xerodermostenosis, sicca syndrome sjogren-gougerot syndrome, sjogren’s syndrome.

S: NIH – (last access: 18 May 2017)