GC: n

S: MN – http://www.medicinenet.com/nonsteroidal_antiinflammatory_drugs/article.htm (last access: 5 February 2016); WebMD – http://www.webmd.com/pain-management/nonsteroidal-anti-inflammatory-drugs-nsaids (last access: 5 February 2016).

N: 1. Origin of NSAID: nonsteroidal anti-inflammatory drug
First Known Use: 1982.
2. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to relieve pain and inflammation from arthritis and related conditions. They work by blocking hormone-like substances called prostaglandins, which are involved in pain and inflammation. Traditional NSAIDs block prostaglandins by inhibiting two enzymes, cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).
3. By doing so, they leave the stomach vulnerable to ulcers and bleeding. Celecoxib (Celebrex) blocks only the COX-2, enzyme. It is less likely to damage the stomach.
4. Every NSAID may increase the risk of serious blood clots, heart attacks and stroke, which can increase with higher doses and long-term use. Although all NSAIDs work similarly to ease pain and inflammation, finding the most appropriate one for you may take some trial and error.
5. Abbreviations: NSAID, NAID.

S: 1. MW – http://www.merriam-webster.com/dictionary/NSAID (last access: 5 February 2016). 2, 3 & 4. arth – http://www.arthritis.org/living-with-arthritis/treatments/medication/drug-types/nsaids/drug-guide-nsaids.php (last access: 5 February 2016). 5. MEDNT – http://www.medicalnewstoday.com/articles/179211.php (last access: 5 February 2016).

GV: non-steroidal anti-inflammatory drug

F: http://www.nhs.uk/Conditions/Anti-inflammatories-non-steroidal/Pages/Introduction.aspx (last access: 5 February 2015)

SYN: non-steroidal anti-inflammatory agent

S: MEDNT – http://www.medicalnewstoday.com/articles/179211.php (last access: 5 February 2016); DTMe (last access: 5 February 2016).

CR: diclofenac, steroid.