multiple sclerosis

GC: n

S: WHO - http://www.who.int/vaccine_safety/committee/topics/hepatitisb/multiple_sclerosis/Jun_2002/en/(external link) (last access: 5 November 2017); MAYO - https://goo.gl/NYNsef(external link) (last access: 1 November 2017); NHS - https://www.nhs.uk/conditions/multiple-sclerosis/(external link) (last access: 1 November 2017).

N: 1. - sclerosis (n): "morbid hardening of the tissue," late 14c., from Medieval Latin sclirosis "a hardness, hard tumor," from Greek sklerosis "hardening," from skleros "hard". Figurative use by 1954.
- multiple (adj): from French multiple (14c.),"involving many parts" (1640's), from Late Latin multiplus "manifold", from Latin multi- "many, much" + -plus "-fold".
2. A chronic progressive disease of the central nervous system characterized by loss of some of the myelin sheath surrounding certain nerve fibres and resulting in speech and visual disorders, tremor, muscular incoordination, partial paralysis, etc.
3. The abbreviation MS is also used.
4. It was first attested in 1877. It is called this way because it occurs in patches.
5. The cause of MS remains unclear, but in many cases there is evidence of a genetic component. In fact, nearly five dozen different genetic variations have been associated with increased risk for the disease.
6. There is no cure for MS, but a number of medications, such as corticosteroids, are used to alleviate symptoms.
7. Women are about twice as likely as men are to develop MS.
8. Cultural Interrelation: We can find a reference to the MS in the film Go now (1996) directed by Michael Winterbottom.

S: 1. OED - https://goo.gl/GeFtsd;(external link) https://goo.gl/EjfNxc(external link) (last access: 2 November 2017). 2 & 3. CED - https://goo.gl/NFQ2i7(external link) (last access: 1 November 2017). 4. OED - https://goo.gl/6i4iFN(external link) (last access: 01 November 2017). 5 & 6. EncBrit - https://goo.gl/A2TT2B(external link) (last access: 01 November 2017). 7. MAYO - https://goo.gl/NYNsef(external link) (last access: 1 November 2017). 8. LMS - https://goo.gl/5FKAwL(external link) (last access: 1 November 2017).

SYN: disseminated sclerosis, focal sclerosis, insular sclerosis.

S: GDT - https://goo.gl/5aAFgM(external link) (last access: 1 November 2017)

CR: amyotrophic lateral sclerosis, arteriosclerosis, dysesthesia.


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